From the back cover:
Following a magical mix-up, British Magizoologist Newt Scamander unwittingly finds himself on a chase around New York City looking for magical beasts. To set things right, Newt has to track down his escaped magical creatures with the help of aspiring baker Jacob Kowalski, as well as Tina and Queenie Goldstein, two witches who work for the Magical Congress of the United States of America. This chance meeting of characters leads to an action-packed adventure Newt won't soon forget.